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DOI: 10.1055/a-2591-9608
Single-Stage Quadruple Valve Replacement with Mechanical and Bioprosthetic Valves: An 8-Year Follow-up Study from India
Funding None.

Abstract
Background
Congenital heart disease, repaired or unrepaired, requires lifelong follow-up. Carcinoid disease, rheumatic heart disease, and infective endocarditis can damage all four cardiac valves. Multiple valve replacement has a poor outcome.
Case Description
A 23-year-old male underwent single-stage quadruple valve (mechanical [mitral and aortic] and bioprosthetic [tricuspid and pulmonary]) replacement due to rheumatic carditis and surgical complications. Over 8 years of follow-up, he is asymptomatic, has no prosthetic valve-related complications, and has improved cardiac function.
Conclusion
Single-stage quadruple valve replacement with mechanical and bioprosthetic valves has a good long-term outcome. To the best of our knowledge, this is the longest follow-up study from India.
Note
This study was presented at CSI Frankfurt on June 21, 2024, as a poster presentation.
Publication History
Received: 22 February 2025
Accepted: 07 April 2025
Accepted Manuscript online:
22 April 2025
Article published online:
26 May 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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